| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Anti D | Teva Ltd. | 300ug | 2ml | inj | KES 4,400 | ||
| KamRho D | Kamada | 300ug | 2ml | inj | KES 4,600 | ||
| Partobulin | CreamMapple | 250 ug | 1s | inj | KES 3,000 | ||
| RhoGham | Kedrion | 300ug | 1s | inj | KES 4,500 |
| Anti-D immunoglobulin More info | |
|---|---|
| Mode Of Action | For anti-D the mechanism of inhibition of antibody synthesis is unclear, but rapid destruction and clearance of Rh-positive cells from the circulation seem to play a role. |
| Drug Indication | Prophylaxis of Rhesus sensitization. |
| Precautions | Avoid live virus vaccination for at least 3 months after administration of this vaccine. |
| Contra-Indications | Rh+ve mother, Rh-ve mother who has given birth to Rh-ve baby, mother already having anti-D antibodies, IV administration, babies. |
| Side Effects | Anaphylactic reactions, headache, fever, flush, chills. |
| Dosage | Full-term Delivery: 300 ug within 72 hrs of delivery (e.g. birth, abortion) if there are no pre-existing anti-D antibodies. (It can still be administered even if a longer period has elapsed). Prophylactic doses of 300ug on 28th and 34th weeks of gestation and 300ug within 72 hrs of delivery for the un-sensitized patients. For transplacental bleed in excess of 4-5ml fetal red cells: administer 60 -75 ug per ml fetal red cells. For stillbirth, abortion, amniocentesis and other sensitizing episodes up to 20 wks gestation: 150 ug per episode within 72 hrs. In case of incompatible blood transfusion: 75 ug / ml of transfused Rh (+ve) blood. |
| Special Information | Over 90% of Rh (-ve) women having Rh (+ve) offspring do not form anti-D antibodies. As it is not possible to predict who will make antibodies, all Rh(-ve) women with an Rh(+ve) baby must be given prophylaxis.Since Rh antigens are detectable in an embryo a few weeks after conception, anti-D immunoglobulin should also be given to Rh(-ve) women who have aborted. |
| Drug Category | DRUGS ACTING ON INFECTIONS |
| Drug Sub-Category | Sera & Immunoglobulins |